Anatomically divided into: 1-Cardia: Contain cardiac mucous glands 2-Fundus & body: Have the same histologic structure 3-Pyloric: Contain pyloric mucous glands Histologically, the wall is formed of 4 layers: 1-Mucosa 2-Submucosa 3-Musculosa 4-Serosa
I-Mucosa
Characterized by: Thick, Dark Have folds called rugae Formed of: 1-Epith.: Simple columnar [Mucous surface cells] 2-Lamina propria: Loose C.T, contain FUNDIC GLANDS** 3-Muscularis mucosa: 2 layers of smooth ms. [inner circular & Outer longitudinal]
II-Submucosa
Loose C.T containing: Blood vessels, lymph vessels Lymphocytes, macrophages & mast cells Meissner’s nerve plexus
III-Musculosa
Three layers of smooth ms.: Inner oblique, Middle circular, and Outer longitudinal Auerbach’s nerve plexus: -Between circular & longitudinal muscle layers -Regulate peristalsis of musculosa
IV-Serosa
Loose C.T, covered with simple squamous epith. [mesothelium]
Characters of Fundic Glands
Simple branched tubular
Occupy most of mucosal thickness
Perpendicular to surface
Highly crowded with little C.T in between
Open on surface by narrow & short pits [Ducts]
Ratio between pits & gland is 1:4
Formed of isthmus, neck & base
